NOGO could go far
نویسندگان
چکیده
منابع مشابه
Nogo on the Go
Growth inhibition in the central nervous system (CNS) is a major barrier to axon regeneration. Recent findings indicate that three distinct myelin proteins, myelin-associated glycoprotein (MAG), Nogo, and oligodendrocyte-myelin glycoprotein (OMgp), inhibit axon growth by binding a common receptor, the Nogo66 receptor (NgR), and likely converge on a common signaling cascade.
متن کاملLearning Go/NoGo Terrain Classification
This paper presents a software system for imagebased terrain classification that mimics a human supervisor’s segmentation and classification of training images into “Go” and “NoGo” regions. The system identifies a set of image chips in the training images that span the range of terrain appearance. It then uses these exemplars to segment novel images and assign fuzzy Go/NoGo classification. Syst...
متن کاملNo Nogo Now Where to Go?
Nogo-A, a reticulon protein expressed by oligodendrocytes, contributes to the axonal growth inhibitory action of central myelin in growth cone collapse and neurite outgrowth in vitro assays, and antibody and inhibitor studies have implicated a role for Nogo in regeneration in the adult CNS in vivo. Three independent labs have now produced Nogo knockout mice with, quite unexpectedly, three diffe...
متن کاملHow Far Could We Go with Open Data – A Case Study for TRPV1 Antagonists
Publicly open databases of small compounds have become an indispensable tool for chemoinformaticians for collection and preparation of datasets suitable for drug discovery questions. Since these databases comprise compounds coming from structure-activity relationship (SAR) studies performed by different research groups, they are very diverse with respect to the biological assays used. In the pr...
متن کاملHow Far Could Gps Go in Monitoring Structural Response to Wind Events?
Two techniques have been applied increasingly in recent years for monitoring the response of tall buildings to wind: the traditional accelerometer and GPS. The focus of this paper is to study how the two sensors perform relative to each other, and in particular the value of GPS measurements in improving wind effect modelling. The test site is a 192m high office tower in downtown Sydney (with a ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Science-Business eXchange
سال: 2011
ISSN: 1945-3477
DOI: 10.1038/scibx.2011.756